Most common forms of hair loss (alopecia) are caused by aberrant hair follicle cycling and changes in hair follicle morphology. However, current treatments for alopecia do not specifically target these processes. Adipose-derived stromal vascular cells (ADSVCs) that can be harvested from fat cells are one of the latest breakthroughs in the aesthetic field.Stem Cells in Tx Alopecia May 2018
Platelet-rich plasma (PRP) is an autologous concentration of human platelets contained in a small volume of plasma with haemostatic and tissue repairing effects. Being enriched by various growth factors, PRP has become the focus of attention in numerous fields of medicine. Androgenic alopecia (AGA) is a common chronic hair loss disorder, characterised by progressive hair lossPRP vs. Placebo June 2017
MeAdipose-derived stem cells (ASCs) have stimulatory effects on dermal papilla (DP) cells to promote hair-growth. For example, ASCs secrete multiple growth factors, such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factors (bFGF), which can increase the
proliferation of DP cells.
Activation of the Wnt/β-catenin signaling pathway plays an important role in hair follicle morphogenesis and hair growth. Recently, low-level laser therapy (LLLT) was evaluated for stimulating hair growth in numerous clinical studies, in which 655-nm red light was found to be most effective and practical for stimulating hair growth.
Platelet-rich plasma (PRP) has emerged as a new treatment modality in regenerative plastic surgery,
and preliminary evidence suggests that it might have a beneficial role in hair regrowth. Here, we report
the results of a randomized, evaluator-blinded, placebo-controlled, half-head group study to
compare, with the aid of computerized trichograms, hair regrowth with PRP versus placebo. The
safety and clinical efficacy of autologous PRP injections for pattern hair loss were investigated.
PRP, prepared from a small volume of blood, was injected on half of the selected patients’ scalps with
pattern hair loss. The other half was treated with placebo.