Brown and white adipose tissue is a source of mesenchymal stem cells, specifically adipose-derived stem cells (ADSCs). It is an inexpensive, unlimited reservoir of stem cells. From
300 ml of adipose tissue, 2-3 × 108 ADSCs can be obtained.
In Association with National Society of Regenerative Medicine
Non Healing Wounds
Wound healing is an important but complicated process in human or animal, containing a multifaceted process governed by sequential yet overlapping phases, including hemostasis/ inflammation phase, proliferation phase, and remodeling phase.
Stem Cells in Wound Heling Feb 2018In Greek mythology, Achilles, the demigod hero, is almost invulnerable except for his Achilles heel, whose injury resulted in his death. How could a tendon injury take such a prominent place in Greek mythology? This injury was obviously such a crucial and inexplicable event that it was extensively honored in the legendary Iliad of Homer.
Stem Cells in Achilles Tendon Healing 2017Skin, the largest organ of the body, has multiple important functions, such as acts as a barrier to foreign pathogens, regulates body temperature, supplies sensation, and prevents dehydration of the body.
Stem Cells in Wound healingDiabetic foot ulcer is a chronic, refractory, frequent complication in diabetic patient. Its treatment often requires multidisciplinary joint efforts, diverse strategies have been adopted to address this annoying issue, including stem cell-based therapy/acellular dermal matrix/negative pressure wound therapy etc.
Stem Cells for Diabetic Foot UlcerPresenting the results at the European Association for the Study of Diabetes (EASD) 2016 Annual Meeting, Ahmed Albehairy, MD, from Mansoura University, Egypt, said: “In patients who received the mesenchymal stem cells, ulcer reduction was found to be significantly higher compared with patients on conventional treatment after both 6 weeks and 12 weeks of follow-up. This is despite the fact that initial ulcer size was larger in the stem-cell–treated group.”
Nearly 50% Reduction in Diabetic Foot Ulcers With Stem CellsWe reviewed the background information and previous clinical studies that considered the use of allogeneic
amniotic tissue and fluid (granulized amniotic membrane and amniotic fluid) in the treatment of chronic
diabetic foot wounds. This innovation represents a relatively new approach to wound management by
delivering a unique allograft of live human cells in a nonimmunogenic structural tissue matrix. Developed to
fill soft tissue defects and bone voids and to convey antimicrobial and anti-inflammatory capabilities,
granulized amniotic membrane and amniotic fluid does not require fetal death, because its procurement is
performed with maternal consent during birth. In the present investigation, 20 chronic wounds (20 patients)
that had been treated with standard wound therapy for a mean of 36.6 31.58 weeks and with a mean
baseline area of 10.15 19.54 cm2 were followed up during a 12-week observation period or until they healed.
A total of 18 of the wounds (90%) healed during the 12-week observation period, and none of the wounds
progressed to amputation. From our experience with the patients in the present case series, we believe that
granulized amniotic membrane and amniotic fluid represents a useful option for the treatment of chronic
diabetic foot wounds.
Copyright ©2018 All Rights Reserved.
Designed by NWOL