The process of cartilage destruction in the diarthrodial joint is progressive and irreversible. This destruction is extremely difficult to manage and frustrates researchers, clinicians, and patients. Patients often take medication to control their pain. Surgery is usually performed when pain becomes uncontrollable or joint function completely fails.Stem Cell Based Cartilage Regeneration March 2018
Alzheimer’s disease (AD), a progressive neurodegenerative disorder featuring memory loss and cognitive impairment, is caused by synaptic failure and the excessive accumulation of misfolded proteins. Many unsuccessful attempts have been made to develop new small molecules or antibodies to intervene in the disease’s pathogenesis.Stem Cells in Alzheimer's Dis Mar 2018
Resulting from a various etiologies, the most notable remains ischemia; heart failure (HF) manifests as the common end pathway of
many cardiovascular processes and remains among the top causes for hospitalization and a major cause of morbidity and mortality
worldwide. Current pharmacologic treatment for HF utilizes pharmacologic agents to control symptoms and slow further
Cell therapy continues to attract growing interest as a promising approach to treat a variety of diseases. Mesenchymal stem cells (MSCs) have been one of the most intensely studied candidates for cell therapy.MSC's to Improve Bone Healing April 2017
As the regeneration technologies developing, stem cell therapy has been a promising and attractive way to enhance tissue regeneration and problem wound healing. Stem cells are characterized by their multipotency and capacity for self-renewal, and their ability to secrete pro regenerative cytokines, making them a promising choice for the tissue regeneration.MSC's in Wound Healing March 2018
Healing and regeneration of bone injuries, particularly those that are associated with large bone defects, are a complicated process. There is growing interest in the application of osteoinductive and osteogenic growth factors and mesenchymal stem cells (MSCs) in order to significantly improve bone repair and regeneration.MSC's in Bone Regenerative Medicine June 2017
Erectile dysfunction (ED) is the most common sexual disorder that men report to healthcare providers, and is the male sexual dysfunction that has been most investigated. Current treatments for ED focus on relieving the symptoms of ED and therefore tend to provide a temporary solution rather than a cure or reversing the cause.Stem Cell Therapy in Erectile Dysfunction Sept. 2013
Articular cartilage is a hyaline lining on the articular surface of bone ends. It cushions external impacts and reduces
friction between bones to enable smooth and painless joint motion. Chondrocytes are the only resident cell type in cartilage and comprise 1–5% of articular cartilage. These cells produce collagen, proteoglycans, and hyaluronic acid, which are components of the extracellular matrix (ECM) and underlie the mechanical properties of cartilage.
Multiple sclerosis (MS) is an immune-mediated infammatory disease in which the immune system progressively destroys its own myelinated axons in the central
nervous system, in episodes lasting from a few months to many years in duration. Te eventual demyelination and axonal degeneration can cause serious and debilitating motor, sensory, balance and cognitive problems, disability, serious complications, and negatively impact quality of life.