Potential role of herbal remedies in stem cell therapy: proliferation and differentiation of human mesenchymal stromal cells

Stem cell therapy has revolutionized modern clinical therapy with the potential of stem cells to differentiate into
many different cell types which may help to replace different cell lines of an organism. Innumerous trials are carried
out to merge new scientific knowledge and techniques with traditional herbal extracts that may result in less toxic,
affordable, and highly available natural alternative therapeutics. Currently, mesenchyamal stromal cell (MSC) lines
are treated with individual and mixtures of crude herbal extracts, as well as with purified compounds from herbal
extracts, to investigate the mechanisms and effects of these on stem cell growth and differentiation. Human MSCs
(hMSCs) possess multilineage, i.e., osteogenic, neurogenic, adipogenic, chondrogenic, and myogenic, differentiation
abilities.